This initiative funds early-stage translational research activities including prototype testing and design modification, assay development for diagnostic targets, and research tool development for HLBS diseases. It supports projects aiming to transition basic science discoveries into viable diagnostic or therapeutic candidates cleared for human testing, preparing them for subsequent in vivo testing and further development.
Eligible applicants include a wide range of U.S.-based institutions such as higher education, nonprofits, small businesses, tribal governments, and various government entities. Non-domestic entities are not eligible, but foreign components of U.S. organizations are allowed.