Supports fundamental research on living systems at atomic to cellular scales, emphasizing mechanistic insights, quantitative and predictive models, and transformative ideas. Encourages interdisciplinary approaches across molecular biophysics, genetic mechanisms, cellular dynamics, and systems/synthetic biology. Welcomes projects integrating across scales, disciplines, and biological subfields, including the Integrative Research in Biology track.
Proposals may be submitted by US-based institutions of higher education, non-profit non-academic organizations directly associated with educational or research activities. International branch campuses require justification for project activities performed abroad.