This opportunity funds biologic-based therapeutic discovery and development targeting nervous system disorders, including proteins, antibodies, peptides, gene-based therapies, cell therapies, and emerging microbial therapies. Awardees collaborate with NIH consultants and may use NIH contract research organizations for manufacturing, pharmacokinetics, toxicology, and phase I clinical testing. Intellectual property rights remain with awardees, enabling control over patent prosecution and licensing.
Eligible applicants include a wide range of organizations such as state and local governments, tribal organizations, institutions of higher education, nonprofits, for-profit organizations, small businesses, and various federally recognized and non-recognized entities including U.S. territories and f