This funding opportunity supports clinical trials designed to evaluate the effectiveness of therapeutic and service delivery interventions for post-acute management of mental health conditions in youth, adults, and older adults. Trials should be statistically powered to provide definitive evidence on intervention effectiveness and explore moderators, mediators, and mechanisms of action. The focus is on interventions matched to illness stage to maintain treatment gains, manage residual symptoms, prevent relapse, and promote adherence for optimal long-term outcomes.
Eligible applicants include a wide range of organizations such as nonprofits, for-profits (excluding small businesses), institutions of higher education, government entities at various levels, tribal organizations, and small businesses. Specific eligibility details are provided in the funding announ
