This funding opportunity supports research projects conducting clinical trials to evaluate the effectiveness of therapeutic and service delivery interventions for post-acute management of mental health conditions in youth, adults, and older adults. Trials should be statistically powered to definitively assess intervention effectiveness and test hypotheses about moderators, mediators, and mechanisms of action. Interventions must be matched to illness stage and focus on consolidating treatment gains, managing residual symptoms, preventing relapse, and promoting adherence for optimal long-term ou
Eligible applicants include a wide range of organizations such as nonprofits, for-profits, small businesses, tribal governments, educational institutions, state and local governments, and federal agencies, including certain minority-serving institutions and non-U.S. entities.