This grant supports research focused on screening and functionally validating genetic variants associated with human congenital anomalies, intellectual developmental disabilities, and inborn errors of metabolism. Funded activities include using in-silico tools, animal models, in vitro systems, and multi-pronged approaches to characterize variants identified through public genomic databases and individual efforts, addressing the gap between variant identification and understanding their phenotypic effects.
Eligible applicants include a wide range of organizations such as Native American tribal organizations, nonprofits, small businesses, institutions of higher education, government entities, and various minority-serving institutions. Both domestic and certain non-domestic entities may apply.
