This opportunity supports neuroscience investigators in advancing small molecule drug discovery and development projects targeting nervous system disorders. Funded activities include conducting disease- or target-specific assays and models in applicants' own labs, collaborating with NIH consultants, and utilizing NIH contract research organizations for medicinal chemistry, pharmacokinetics, toxicology, GMP synthesis, and phase I clinical testing. Projects may enter at discovery or development stages and progress through IND-enabling toxicology and phase I trials. Awardees retain IP rights for
Eligible applicants include a wide range of entities such as federally recognized Native American tribal governments, county and city governments, independent school districts, public housing authorities, private and public higher education institutions, nonprofits, small businesses, for-profit orga
