Supports pilot effectiveness trials for mental health interventions that optimize preventive and therapeutic treatments with prior efficacy evidence. Encourages development and preliminary testing of innovative service delivery approaches. Studies must explicitly evaluate intervention mechanisms underlying clinical or service outcomes, consistent with experimental therapeutics approaches. Clinical trials are required.
Eligible applicants include a wide range of organizations such as nonprofits, for-profits (excluding small businesses), tribal governments, educational institutions, and various government entities. Specific eligibility details are provided in the announcement.
