This funding opportunity supports research programs aimed at advancing discovery, preclinical development, and proof of concept testing of novel candidate agents and neurostimulation approaches to treat mental disorders, substance use disorders, and alcohol use disorder. It also funds development of novel ligands and circuit-engagement devices to characterize or validate drug/device targets. Partnerships between academia and industry are strongly encouraged. The program supports multiple projects directed toward a major objective requiring a multidisciplinary and often long-term approach. Clin
Eligible applicants include a wide range of U.S. organizations such as public and private institutions of higher education, nonprofits, government entities, small businesses, tribal governments and organizations, and for-profit organizations. Specific eligibility details should be confirmed with the
