This funding opportunity supports investigators in discovering and developing novel small molecules as in vivo chemical probes for brain targets. It emphasizes projects that provide new insights into disease-related biological targets and biological processes relevant to mental health, drug abuse, eye health, and aging. Applicants should have validated starting compounds and bioassays for testing new analogs. Clinical trials are not allowed.
Eligible applicants include a wide range of organizations such as private higher education institutions, tribal organizations, small businesses, nonprofits, for-profit organizations, various government entities, and independent school districts within the United States.