This funding opportunity supports investigators aiming to discover and develop novel small molecule chemical probes for in vivo use targeting brain-related biological processes. It emphasizes projects that provide new insights into disease-related biological targets and mechanisms relevant to mental health, drug abuse, eye health, and aging. Applicants should have validated starting compounds and the capability to optimize and test new analogs. Clinical trials are not allowed.
Eligible applicants include a wide range of organizations such as private higher education institutions, tribal organizations, small businesses, government entities, nonprofits, and foreign organizations. Both domestic and non-domestic entities may apply, including foreign components of U.S. organiz
